A prospective and randomised trial of efficacy and safety of transdermal oxybutynin versus oral oxybutynin in the management of children with overactive bladder
نویسندگان
چکیده
منابع مشابه
Transdermal oxybutynin in the treatment of overactive bladder
Overactive bladder is a dreadful syndrome that affects a considerable number of patients. Antimuscarinics are the mainstay of pharmacotherapy for this condition. Transdermal (TD) oxybutynin (OXY) bypasses the first-pass metabolism and reduces the formation of N-desethyloxybutynin, a compound believed to be associated with anticholinergic side effects. The 3.9 mg matrix TD system is applied twic...
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OBJECTIVE This subgroup analysis of a phase-3 study evaluated the efficacy and safety of oxybutynin chloride topical gel (OTG) in women with overactive bladder syndrome (OAB). STUDY DESIGN Women (n = 704) with urgency-predominant urinary incontinence received OTG or placebo for 12 weeks. The primary endpoint was change from baseline to last observation in number of daily incontinence episodes...
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objective: to evaluate the efficacy and side effects of oxybutinin in comparison to tolterodine in treatment of overactive bladder (oab) with detrussor overactivity (doa) in iranian women. materials and methods: one hundred iranian old women with clinical symptoms of oab who show ido in the filling cystometry participated in this randomized double-blinded parallel-group by using two kinds of th...
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ژورنال
عنوان ژورنال: European Urology Open Science
سال: 2020
ISSN: 2666-1683
DOI: 10.1016/s2666-1683(20)33350-4